Alberta researchers recently isolated and cloned a DNA sequence that encodes a 53-amino acid protein, bovine epidermal growth factor (EPG). Previous research in rodents and rabbits demonstrated that EPG has the ability to stimulate proliferation of a number of cell types, including the epithelial cells that line the intestine. This work also indicated that EPG can improve the absorption of nutrients across intestinal membranes. Furthermore, oral administration of EPG reduced the incidence of intestinal infections and prevented weight gain reduction that results from infection. Future research by Alberta scientists will focus on the biological effect of bovine EPG in cattle. The objective will be to determine if EPG has the ability to enhance the efficiency of nutrient absorption and reduce intestinal disease in beef cattle. The authors stated that because of the positive effects of EPG on intestinal function, it may have great potential as a feed additive in cattle diets (Bilodeau-Goeseels et al. 2003. Agriculture and Agri-Food Canada, Lethbridge Research Centre).